发明申请
US20090053300A1 MONOCLONAL ANTIBODY, GENE ENCODING THE ANTIBODY, HYBRIDOMA, PHARMACEUTICAL COMPOSITION, AND DIAGNOSTIC REAGENT
审中-公开
单克隆抗体，编码抗体，杂交物，药物组合物和诊断试剂的基因
- 专利标题： MONOCLONAL ANTIBODY, GENE ENCODING THE ANTIBODY, HYBRIDOMA, PHARMACEUTICAL COMPOSITION, AND DIAGNOSTIC REAGENT
- 专利标题（中）： 单克隆抗体，编码抗体，杂交物，药物组合物和诊断试剂的基因
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申请号： US12279160申请日： 2007-02-23
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公开(公告)号： US20090053300A1公开(公告)日： 2009-02-26
- 发明人: Saiko Hosokawa , Yoko Hirakawa , Kazumasa Fukuda , Rieko Nakamura , Yoshiro Saikawa , Masahiko Aoki , Koichiro Kumai
- 申请人： Saiko Hosokawa , Yoko Hirakawa , Kazumasa Fukuda , Rieko Nakamura , Yoshiro Saikawa , Masahiko Aoki , Koichiro Kumai
- 申请人地址： JP Osaka-shi JP Tokyo
- 专利权人： MITSUBISHI TANABE PHARMA CORPORATION,KEIO UNIVERSITY
- 当前专利权人： MITSUBISHI TANABE PHARMA CORPORATION,KEIO UNIVERSITY
- 当前专利权人地址： JP Osaka-shi JP Tokyo
- 优先权： JP2006-046974 20060223
- 国际申请： PCT/JP2007/053391 WO 20070223
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/00 ; C12N15/13 ; C12N15/85 ; A61K39/44 ; A61K9/127 ; C12N5/10 ; C12N5/16
摘要：
Disclosed is a monoclonal antibody which has a heavy chain variable region containing amino acid sequences depicted in SEQ ID NOs:74, 76 and 78 and a light chain variable region containing amino acid sequences depicted in SEQ ID NOs:80, 82 and 84. The monoclonal antibody can be used as a cancer therapeutic agent which acts selectively on a cancer tissue of non-small lung cancer, pancreatic cancer, gastric cancer or the like.
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