发明申请
- 专利标题： Method For Improvement Of Differentiation Of Mesenchymal Stem Cells Using A Double-Structured Tissue Implant
- 专利标题（中）： 使用双结构组织植入物改善间充质干细胞分化的方法
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申请号： US12195255申请日： 2008-08-20
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公开(公告)号： US20090069903A1公开(公告)日： 2009-03-12
- 发明人: Sonya Shortkroff , Joseph Khoury , Laurence J.B. Tarrant , Hans P.I. Claesson , Robert Lane Smith
- 申请人： Sonya Shortkroff , Joseph Khoury , Laurence J.B. Tarrant , Hans P.I. Claesson , Robert Lane Smith
- 申请人地址： US MA Waltham
- 专利权人： HISTOGENICS CORPORATION
- 当前专利权人： HISTOGENICS CORPORATION
- 当前专利权人地址： US MA Waltham
- 主分类号： A61F2/02
- IPC分类号： A61F2/02 ; A61B17/08
摘要：
A double-structured tissue implant (DSTI) and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant for differentiation, growth and transformation of cells, stem cells, mesenchymal stem cells and bone marrow stem cells. DSTI comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold.
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