发明申请
- 专利标题: Modified Lecithin-Cholesterol Acyltransferase Enzymes
- 专利标题(中): 改性卵磷脂 - 胆固醇酰基转移酶
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申请号: US12179815申请日: 2008-07-25
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公开(公告)号: US20090081182A1公开(公告)日: 2009-03-26
- 发明人: Tom BOONE , David P. MEININGER , Margrit SCHWARZ , Bei SHAN , Wenyan SHEN , Mingyue ZHOU
- 申请人: Tom BOONE , David P. MEININGER , Margrit SCHWARZ , Bei SHAN , Wenyan SHEN , Mingyue ZHOU
- 申请人地址: US CA THOUSAND OAKS
- 专利权人: AMGEN INC.
- 当前专利权人: AMGEN INC.
- 当前专利权人地址: US CA THOUSAND OAKS
- 主分类号: A61K38/45
- IPC分类号: A61K38/45 ; C12N9/10 ; A61P9/00
摘要:
The invention provides compounds, pharmaceutical compositions and methods for treating atherosclerosis, coronary heart disease, thrombosis, and for decreasing or prevention of accumulation of cholesterol in a subject by modifying LCAT polypeptide.
公开/授权文献
- US08168416B2 Modified lecithin-cholesterol acyltransferase enzymes 公开/授权日:2012-05-01
信息查询
IPC分类: