Invention Application
US20090093631A1 Processes for the preparation of a linezolid intermediate, linezolid hydroxide
审中-公开
制备利奈唑胺中间体,利奈唑烷氢氧化物的方法
- Patent Title: Processes for the preparation of a linezolid intermediate, linezolid hydroxide
- Patent Title (中): 制备利奈唑胺中间体,利奈唑烷氢氧化物的方法
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Application No.: US12231769Application Date: 2008-09-05
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Publication No.: US20090093631A1Publication Date: 2009-04-09
- Inventor: Ben-Zion Dolitzky , Nurit Perlman , Marina Kalujny
- Applicant: Ben-Zion Dolitzky , Nurit Perlman , Marina Kalujny
- Main IPC: C07D413/10
- IPC: C07D413/10

Abstract:
Provided are methods for the enantiomeric purification of Linezolid hydroxide, comprising providing a solution or a slurry of Linezolid hydroxide and a solvent selected from alcohols and ketones and crystallizing Linezolid hydroxide from the solution or slurry to obtain Linezolid hydroxide with a low content of S isomer.
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