发明申请
- 专利标题： process for the preparation of escitalopram
- 专利标题（中）： 艾司西酞普兰的制备方法
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申请号： US11989621申请日： 2006-07-20
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公开(公告)号： US20090099375A1公开(公告)日： 2009-04-16
- 发明人: Vipin Kumar Kaushik , Umar Khan Mohammed , Sivakumaran Meenakshisunderam
- 申请人： Vipin Kumar Kaushik , Umar Khan Mohammed , Sivakumaran Meenakshisunderam
- 优先权： IN1014/CHE/2005 20050727
- 国际申请： PCT/IB2006/002050 WO 20060720
- 主分类号： C07D307/81
- IPC分类号： C07D307/81
摘要：
The present invention relates to an improved process for the preparation of Escitalopram of the Formula (I), which comprises, isolation of Diol compound as an oxalate salt, resolution of Diol compound and cyclization of resolved compound of Formula (VII). The present invention provides a process to obtain pure Diol compound by preparing its Oxalate salt, which is useful for resolution of enantiomers.
公开/授权文献
- US07939680B2 Process for the preparation of Escitalopram 公开/授权日：2011-05-10
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