发明申请
- 专利标题: Selective Vpac2 Receptor Peptide Agonists
- 专利标题(中): 选择性Vpac2受体肽激动剂
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申请号: US11573917申请日: 2005-08-11
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公开(公告)号: US20090118167A1公开(公告)日: 2009-05-07
- 发明人: Bengt Krister Bokvist , John Philip Mayer , Lianshan Zhang , Jorge Alsina-Fernandez , Andrew Mark Vick
- 申请人: Bengt Krister Bokvist , John Philip Mayer , Lianshan Zhang , Jorge Alsina-Fernandez , Andrew Mark Vick
- 申请人地址: US IN Indianapolis
- 专利权人: Eli Lilly and Company Patent Division
- 当前专利权人: Eli Lilly and Company Patent Division
- 当前专利权人地址: US IN Indianapolis
- 国际申请: PCT/US05/28591 WO 20050811
- 主分类号: A61K38/17
- IPC分类号: A61K38/17 ; C07K14/475
摘要:
The invention provides VPAC2R peptide agonists coupled to at least one polyethylene glycol molecule or derivative thereof, resulting in a biologically active peptide with an extended half-life and a slower clearance when compared to that of unPEGylated peptide.
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