发明申请
- 专利标题: Immune-Modulating Peptide
- 专利标题(中): 免疫调节肽
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申请号: US12246229申请日: 2008-10-06
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公开(公告)号: US20090118197A1公开(公告)日: 2009-05-07
- 发明人: Sung-Ho Ryu , Pann-Ghill Suh , Yoe-Sik Bae , Ji-Young Song
- 申请人: Sung-Ho Ryu , Pann-Ghill Suh , Yoe-Sik Bae , Ji-Young Song
- 申请人地址: KR Kyungsangbuk-do KR Kyungsangbuk-do
- 专利权人: POSCO,POSTECH Foundation
- 当前专利权人: POSCO,POSTECH Foundation
- 当前专利权人地址: KR Kyungsangbuk-do KR Kyungsangbuk-do
- 主分类号: A61K38/08
- IPC分类号: A61K38/08 ; C07K7/06 ; A61P29/00
摘要:
Disclosed are peptides having SEQ ID NOs: 1 to 24 that induce superoxide generation by human monocytes or neutrophils; that induce an intracellular calcium increase by human peripheral blood monocytes or neutrophils; binds to formyl peptide receptor or formyl peptide receptor-like 1; that induce chemotactic migration of human monocytes or neutrophils in vitro; that induce degranulation in formyl peptide receptor expressing cells or formyl peptide receptor-like 1 expressing cells; that stimulate extracellular signal regulated protein kinase phosphorylation via activation of formyl peptide receptor or formyl peptide receptor-like 1; or that stimulate Akt phosphorylation via activation of formyl peptide receptor or formyl peptide receptor-like 1.
公开/授权文献
- US08017572B2 Immune-modulating peptide 公开/授权日:2011-09-13
信息查询
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