发明申请
- 专利标题： Migrastatin analogs in the treatment of cancer
- 专利标题（中）： 米舍他汀类似物治疗癌症
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申请号： US11597678申请日： 2006-05-25
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公开(公告)号： US20090124662A1公开(公告)日： 2009-05-14
- 发明人: Samuel J. Danishefsky , Christoph Gaul , Jon T. Njardarson , Malcolm A.S. Moore , Kaida Wu , David C. Dorn , Mihirbaran Mandal
- 申请人： Samuel J. Danishefsky , Christoph Gaul , Jon T. Njardarson , Malcolm A.S. Moore , Kaida Wu , David C. Dorn , Mihirbaran Mandal
- 国际申请： PCT/US2005/018603 WO 20060525
- 主分类号： A61K31/4523
- IPC分类号： A61K31/4523 ; A61P35/00 ; A61P25/00
摘要：
In one aspect, the present invention provides a method for treating colon and/or ovarian cancer in a subject comprising administering to a subject in need thereof a compound of general formula (I): wherein R1-R6, R, -R, Q, Y1, Y2 and n are as defined herein, wherein the compound is present in an amount effective to inhibit colon and/or ovarian tumor metastasis.
公开/授权文献
- US08957056B2 Migrastatin analogs in the treatment of cancer 公开/授权日：2015-02-17
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