发明申请
- 专利标题： Isoxazole Derivatives and Use Thereof
- 专利标题（中）： 异恶唑衍生物及其用途
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申请号： US12159718申请日： 2006-12-28
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公开(公告)号： US20090131336A1公开(公告)日： 2009-05-21
- 发明人: Jeong Woo Cho , Sang Rak Choi , Sun Gwan Hwang , Kyung Chul Cho , Sung Jin Bae , Tae Sung Koo
- 申请人： Jeong Woo Cho , Sang Rak Choi , Sun Gwan Hwang , Kyung Chul Cho , Sung Jin Bae , Tae Sung Koo
- 优先权： KR10-2005-0135247 20051230; KR10-2006-0135390 20061227
- 国际申请： PCT/KR2006/005837 WO 20061228
- 主分类号： A61K38/05
- IPC分类号： A61K38/05 ; C07D413/04 ; A61K31/422 ; A61K31/5377 ; C07D413/14 ; A61P25/00
摘要：
Disclosed herein are isoxazole derivaties and uses thereof. Serving as agonists of Wnt, the isoxazole derivatives activate Wnt/β-catenin signaling and thus can be used in the treatment and prevention of diseases related to the signal transduction. Also, pharmaceutically acceptable salts of the isoxazole derivatives are disclosed.
公开/授权文献
- US07915297B2 Isoxazole derivatives and use thereof 公开/授权日：2011-03-29
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