发明申请
- 专利标题： Vascular Aging-Predicting Factor and Utilization of the Same
- 专利标题（中）： 血管老化预测因子及其应用
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申请号： US12085656申请日： 2006-10-30
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公开(公告)号： US20090136985A1公开(公告)日： 2009-05-28
- 发明人: Takahito Kondo , Yoshito Ihara , Yoshishige Urata , Shinji Goto , Takaaki Kono
- 申请人： Takahito Kondo , Yoshito Ihara , Yoshishige Urata , Shinji Goto , Takaaki Kono
- 优先权： JP2005-344630 20051129
- 国际申请： PCT/JP2006/321610 WO 20061030
- 主分类号： C12Q1/02
- IPC分类号： C12Q1/02 ; C07K7/06 ; C07K16/18
摘要：
Abstract A predicting factor for vascular aging and an examination method for an early-stage lesion resulting from vascular aging are provided. Specifically, a predicting factor for vascular aging comprising a human apolipoprotein B100 having a glutathionylated thiol group; a method of examining a lesion resulting from vascular aging contain measurement of a human apolipoprotein B100 having a glutathionylated thiol group in the blood sample; an antibody specifically recognizing an apolipoprotein B100 having a glutathionylated thiol group; a diagnostic agent or a diagnostic kit for an early-stage lesion resulting from vascular aging containing an antibody recognizing a human apolipoprotein B100 having a glutathionylated thiol group, are provided.
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