发明申请
- 专利标题： FUSED BICYCLIC PYRIMIDINES
- 专利标题（中）： 熔融双相PYRIMIDINES
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申请号： US12191703申请日： 2008-08-14
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公开(公告)号： US20090137607A1公开(公告)日： 2009-05-28
- 发明人: Swen Holder , Matthias Vennemann , Gerrit Beneke , Armin Zulch , Volker Gekeler , Thomas Beckers , Astrid Zimmermann , Hemant Joshi
- 申请人： Swen Holder , Matthias Vennemann , Gerrit Beneke , Armin Zulch , Volker Gekeler , Thomas Beckers , Astrid Zimmermann , Hemant Joshi
- 优先权： IN1572/MUM/2007 20070814; EP07118736.3-2117 20071018
- 主分类号： A61K31/497
- IPC分类号： A61K31/497 ; C07D487/02 ; A61K31/519 ; A61P35/00
摘要：
Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
公开/授权文献
- US07776864B2 Fused bicyclic pyrimidines 公开/授权日：2010-08-17
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