发明申请
US20090142829A1 Recombinant Constructs And Their Use In Reducing Gene Expression
有权
重组构建体及其在减少基因表达中的应用
- 专利标题： Recombinant Constructs And Their Use In Reducing Gene Expression
- 专利标题（中）： 重组构建体及其在减少基因表达中的应用
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申请号： US12256721申请日： 2008-10-23
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公开(公告)号： US20090142829A1公开(公告)日： 2009-06-04
- 发明人: Kimberly F. Glassman , William J. Gordon-Kamm , Anthony J. Kinney , Keith S. Lowe , Scott E. Nichols , Kevin L. Stecca
- 申请人： Kimberly F. Glassman , William J. Gordon-Kamm , Anthony J. Kinney , Keith S. Lowe , Scott E. Nichols , Kevin L. Stecca
- 专利权人： EI AND PIONEER HI-BRED INTERNATIONAL
- 当前专利权人： EI AND PIONEER HI-BRED INTERNATIONAL
- 主分类号： C12N15/00
- IPC分类号： C12N15/00 ; C12N15/11
摘要：
Recombinant constructs useful for reducing the expression of endogenous mRNA and any substantially similar endogenous mRNA are disclosed. In particular, a recombinant construct comprising, inter alia, a suitable nucleic acid sequence and its reverse complement can be used to alter the expression of any homologous, endogenous RNA (i.e., the target RNA) which is in proximity to this suitable nucleic acid sequence.