发明申请
US20090149449A1 PYRROLOBENZODIAZEPINE DERIVATIVES, COMPOSITIONS COMPRISING THE SAME AND METHODS RELATED THERETO
有权
吡咯烷酮衍生物,包含该衍生物的组合物及其相关方法
- 专利标题: PYRROLOBENZODIAZEPINE DERIVATIVES, COMPOSITIONS COMPRISING THE SAME AND METHODS RELATED THERETO
- 专利标题(中): 吡咯烷酮衍生物,包含该衍生物的组合物及其相关方法
-
申请号: US12370856申请日: 2009-02-13
-
公开(公告)号: US20090149449A1公开(公告)日: 2009-06-11
- 发明人: Paul S. Liu , B. Rao Vishnuvajjala , Kenneth M. Snader , David E. Thurston , Philip W. Howard , Luke Y. Hsiao , Gregory Turner
- 申请人: Paul S. Liu , B. Rao Vishnuvajjala , Kenneth M. Snader , David E. Thurston , Philip W. Howard , Luke Y. Hsiao , Gregory Turner
- 申请人地址: US MD Bethesda US NY Buffalo US MO Kansas City GB London
- 专利权人: The United States of America, as represented by the Secretary, Dept. of Health and Human Service,Starks Associates, Inc.,Midwest Research Institute,Spirogen, Ltd.
- 当前专利权人: The United States of America, as represented by the Secretary, Dept. of Health and Human Service,Starks Associates, Inc.,Midwest Research Institute,Spirogen, Ltd.
- 当前专利权人地址: US MD Bethesda US NY Buffalo US MO Kansas City GB London
- 主分类号: A61K31/551
- IPC分类号: A61K31/551 ; C07D487/04 ; C12N5/06 ; A61P31/04
摘要:
Disclosed are compounds of Formula I wherein X, Y, R1-R7, T1, T2, Z, and p are as described herein; a pharmaceutical composition comprising a compound of Formula I and a carrier; a method of inhibiting growth of a cell, which method comprises administering in an amount effective to inhibit growth a compound of Formula I; a method of treating cancer in a mammal, which method comprises administering in an amount effective to treat cancer a compound of Formula I; a method of treating a viral, parasitic, or bacterial infection of a cell, which method comprises administering in an amount effective to treat a viral, parasitic, or bacterial infection a compound of Formula I; and a method of preparing a compound of Formula I as described herein.
公开/授权文献
信息查询