发明申请
- 专利标题: INHIBITORS OF CARBONIC ANHYDRASE IX
- 专利标题(中): 碳氢化合物抑制剂IX
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申请号: US12350894申请日: 2009-01-08
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公开(公告)号: US20090175794A1公开(公告)日: 2009-07-09
- 发明人: Craig Zimmerman , John W. Babich , John Joyal , Genliang Lu , Kevin P. Maresca , Chris Barone
- 申请人: Craig Zimmerman , John W. Babich , John Joyal , Genliang Lu , Kevin P. Maresca , Chris Barone
- 专利权人: Molecular Insight Pharmaceuticals, Inc.
- 当前专利权人: Molecular Insight Pharmaceuticals, Inc.
- 主分类号: A61K49/00
- IPC分类号: A61K49/00 ; C07F15/00 ; A61K31/555 ; A61P35/00
摘要:
Novel radiopharmaceuticals that are useful in diagnostic imaging and therapeutic treatment of disease characterized by over expression of CA-IX comprise a complex that contains a sulfonamide moiety which is capable of binding the active catalytic site of CA-IX, and a radionuclide adapted for radioimaging and/or radiotherapy:
公开/授权文献
- US08877970B2 Inhibitors of carbonic anhydrase IX 公开/授权日:2014-11-04
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