发明申请
US20090175854A1 Methods of using death receptor ligands and CD20 antibodies
审中-公开
使用死亡受体配体和CD20抗体的方法
- 专利标题： Methods of using death receptor ligands and CD20 antibodies
- 专利标题（中）： 使用死亡受体配体和CD20抗体的方法
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申请号： US11662315申请日： 2005-09-07
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公开(公告)号： US20090175854A1公开(公告)日： 2009-07-09
- 发明人: Avi J. Ashkenazi
- 申请人： Avi J. Ashkenazi
- 申请人地址： US CA South San Francisco
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： US CA South San Francisco
- 国际申请： PCT/US05/32015 WO 20050907
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C12N5/06
摘要：
Methods for using death receptor ligands, such as Apo-2 ligand/TRAIL polypeptides or death receptor antibodies, and CD20 antibodies to treat conditions such as cancer and immune related diseases are provided. Embodiments of the invention include methods of using Apo2L/TRAIL or death receptor antibodies such as DR5 antibodies and DR4 antibodies in combination with CD20 antibodies.