发明申请
US20090176821A1 Amide and Carbamate Derivatives of Alkyl Substituted N-[4-(4-Amino-1H-Imidazo[4,5-C] Quinolin-1-YL)Butyl]Methanesulfonamides and Methods
失效
烷基取代的N- [4-（4-氨基-1H-咪唑并[4,5-C]喹啉-1-YL）丁基]甲磺酰胺和方法的酰胺和氨基甲酸酯衍生物
![Amide and Carbamate Derivatives of Alkyl Substituted N-[4-(4-Amino-1H-Imidazo[4,5-C] Quinolin-1-YL)Butyl]Methanesulfonamides and Methods](/docs/US/2009-07-09/US20090176821A1/abs.jpg.600x600.jpg)
- 专利标题： Amide and Carbamate Derivatives of Alkyl Substituted N-[4-(4-Amino-1H-Imidazo[4,5-C] Quinolin-1-YL)Butyl]Methanesulfonamides and Methods
- 专利标题（中）： 烷基取代的N- [4-（4-氨基-1H-咪唑并[4,5-C]喹啉-1-YL）丁基]甲磺酰胺和方法的酰胺和氨基甲酸酯衍生物
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申请号： US11991686申请日： 2006-09-08
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公开(公告)号： US20090176821A1公开(公告)日： 2009-07-09
- 发明人: Tushar A. Kshirsagar , Shri Niwas , Bryon A. Merrill
- 申请人： Tushar A. Kshirsagar , Shri Niwas , Bryon A. Merrill
- 申请人地址： US NY New York
- 专利权人： COLEY PHARMACEUTICAL GROUP, INC.
- 当前专利权人： COLEY PHARMACEUTICAL GROUP, INC.
- 当前专利权人地址： US NY New York
- 国际申请： PCT/US2006/035181 WO 20060908
- 主分类号： A61K31/437
- IPC分类号： A61K31/437 ; C07D471/14 ; A61P31/12 ; A61P35/00
![Amide and Carbamate Derivatives of Alkyl Substituted N-[4-(4-Amino-1H-Imidazo[4,5-C] Quinolin-1-YL)Butyl]Methanesulfonamides and Methods](/abs-image/US/2009/07/09/US20090176821A1/abs.jpg.150x150.jpg)
摘要：
Amide and carbamate derivatives of N-[4-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamides with an ethyl, methyl, or n-propyl substituent at the 2-position, pharmaceutical compositions containing these compounds, methods of making the compounds, and methods of use of these compounds in modulating the immune system, for inducing cytokine biosyn-thesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.
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