发明申请
- 专利标题: Plant Components and Extracts and Uses Thereof
- 专利标题(中): 植物成分及其提取物及其用途
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申请号: US12295285申请日: 2007-03-29
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公开(公告)号: US20090182028A1公开(公告)日: 2009-07-16
- 发明人: Alois Jungbauer , Svjetlana Medjakovic , Alfred Zöchling
- 申请人: Alois Jungbauer , Svjetlana Medjakovic , Alfred Zöchling
- 申请人地址: AT VIENNA
- 专利权人: G.I.M. GESELLSCHAFT-FUR INNOVATIVE MEDIZIN G.M.B.H NFG OHG
- 当前专利权人: G.I.M. GESELLSCHAFT-FUR INNOVATIVE MEDIZIN G.M.B.H NFG OHG
- 当前专利权人地址: AT VIENNA
- 优先权: EP06450045.7 20060329
- 国际申请: PCT/EP07/02787 WO 20070329
- 主分类号: A61K31/404
- IPC分类号: A61K31/404 ; C07D405/06 ; A61P35/00 ; A61P25/28
摘要:
The present invention provides a medicament comprising a chemical compound according to formula A: wherein R1 is hydrogen, fluorine, chlorine, bromine, hydroxy, mercapto, methoxy, ethoxy, acetoxy, methyl, ethyl, propyl, isopropyl, t-butyl, nitro, amin, N,N-dimethylaminoyl, N,N-diethyl-aminoyl; R2 is hydrogen, a C1-8-alkyl e.g. methyl, ethyl, propyl, isopropyl, butyl, t-butyl; an C1-8-acyl e.g. acetyl, propionyl; R3 is a C5-12-heterocyclic ring, e.g. furanyl, pyranyl, pyrrolyl, pyridinyl, pyrazolyl, thienyl, thiazolyl, indolyl or -0R4 ; R4 is a C5-C12-aromatic ring e.g. phenyl; unsubstituted or substituted in any position with fluorine, chlorine, bromine, methoxy, ethoxy, C1-8-carboxy; Z is OH or 0; and n is 0, 1, 2 or 3, and m is 0, 1, 2 or 3, and its use for the activation of the aryl hydro carbon receptor.
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