A mobility management system and method is provided for efficiently support mobility to an IPv6 based LoWpan. The mobility management method for Internet Protocol version 6 (IPv6) based personal area network (PAN) moving with a mobile router according to the present invention includes detecting, at a mobile terminal, movement of the mobile router; determining whether the movement is an intra-network movement or an inter-network movement, transmitting, when the movement is an intra-network movement, a neighbor discovery request message to a gateway of a currently attached network and receiving a neighbor discovery response message containing a temporary address transmitted by the gateway in response to the neighbor discovery request message. When the movement is an inter-network movement, the gateway receives the binding acknowledgement message from a home agent and establishes a bidirectional tunnel with the home agent.