发明申请
US20090186045A1 USE OF CONSENSUS SEQUENCE AS VACCINE ANTIGEN TO ENHANCE RECOGNITION OF VIRULENT VIRAL VARIANTS
有权
使用符合序列作为疫苗抗原来增强对病毒性VAR变体的识别
- 专利标题： USE OF CONSENSUS SEQUENCE AS VACCINE ANTIGEN TO ENHANCE RECOGNITION OF VIRULENT VIRAL VARIANTS
- 专利标题（中）： 使用符合序列作为疫苗抗原来增强对病毒性VAR变体的识别
-
申请号： US11815203申请日： 2006-01-31
-
公开(公告)号： US20090186045A1公开(公告)日： 2009-07-23
- 发明人: Stuart C. Ray , Andrea L. Cox , David L. Thomas
- 申请人： Stuart C. Ray , Andrea L. Cox , David L. Thomas
- 国际申请： PCT/US2006/003514 WO 20060131
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; C12N15/11 ; C07K14/00 ; A61P31/00 ; C12Q1/70 ; C12N15/00
摘要：
The invention provides consensus sequences for hepatitis C virus 1a and 1b. Also provided are non-synonymous changes for each residue of the consensus sequences. These sequences are useful as compositions or vaccines for prophylactic use or treating HCV-infected individuals. Also provided are methods for lessening the chances for a HCV-infected individual to enter a chronic phase of infection and methods of diagnosing an individual with HCV 1a or HCV 1b infection.
公开/授权文献
信息查询
