发明申请
US20090186093A1 METHODS FOR PREPARING CORE-SHELL COMPOSITES HAVING CROSS-LINKED SHELLS AND CORE-SHELL COMPOSITES RESULTING THEREFROM
有权
用于制备具有交联壳的核心复合材料的方法和结果的核壳复合材料
- 专利标题： METHODS FOR PREPARING CORE-SHELL COMPOSITES HAVING CROSS-LINKED SHELLS AND CORE-SHELL COMPOSITES RESULTING THEREFROM
- 专利标题（中）： 用于制备具有交联壳的核心复合材料的方法和结果的核壳复合材料
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申请号： US12088611申请日： 2006-10-02
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公开(公告)号： US20090186093A1公开(公告)日： 2009-07-23
- 发明人: Futian Liu , Han-Ting Chang , Dominique Charmot , Eric Connor , Paul Mansky , Mingjun Liu
- 申请人： Futian Liu , Han-Ting Chang , Dominique Charmot , Eric Connor , Paul Mansky , Mingjun Liu
- 申请人地址： US CA Santa Clara
- 专利权人： RELYPSA, INC.
- 当前专利权人： RELYPSA, INC.
- 当前专利权人地址： US CA Santa Clara
- 国际申请： PCT/US06/38900 WO 20061002
- 主分类号： A61K9/16
- IPC分类号： A61K9/16
摘要：
The present invention provides methods and compositions for the treatment of ion imbalances using core-shell composites and compositions comprising such core-shell composites. In particular, the invention provides core-shell particles and compositions comprising potassium binding polymers, and core-shell particles and compositions comprising sodium binding polymers, and in each case, pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are also disclosed. The compositions and methods of the invention offer improved approaches for treatment of hyperkalemia and other indications related to potassium ion homeostasis, and for treatment of hypertension and other indicates related to sodium ion homeostasis.
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