发明申请
US20090186809A1 USE OF VALPROIC ACID FOR THE TOPICAL TREATMENT OF MILD TO MODERATE ACNE VULGARIS
审中-公开
用于局部治疗胎儿的有效性用于改善ACNE VULGARIS
- 专利标题： USE OF VALPROIC ACID FOR THE TOPICAL TREATMENT OF MILD TO MODERATE ACNE VULGARIS
- 专利标题（中）： 用于局部治疗胎儿的有效性用于改善ACNE VULGARIS
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申请号： US12295359申请日： 2007-03-13
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公开(公告)号： US20090186809A1公开(公告)日： 2009-07-23
- 发明人: Bernd Hentsch , Sylvia Schwarz
- 申请人： Bernd Hentsch , Sylvia Schwarz
- 申请人地址： DE Frankfurt Am Main
- 专利权人： TOPOTARGET GERMANY AG
- 当前专利权人： TOPOTARGET GERMANY AG
- 当前专利权人地址： DE Frankfurt Am Main
- 优先权： EP06006847.5 20060331
- 国际申请： PCT/EP2007/002201 WO 20070313
- 主分类号： A61K38/12
- IPC分类号： A61K38/12 ; A61K31/19 ; A61K31/165 ; A61K38/00
摘要：
The present invention provides a surprising therapeutic beneficial use for the topical application of valproic acid as a single agent therapy for patients suffering from mild to moderate acne vulgaris. Topically applied VPA has a clinical efficacy comparable to that of the marketed standard medication for this indication, isotretinoin. Furthermore, topically applied VPA is on average well to very well tolerated. The invention relates to the topical medical use of VPA for the treatment of acne vulgaris and comprises the topical application of VPA or of a pharmaceutically acceptable salt thereof.
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