发明申请
US20090191221A1 ANTIBODIES RECOGNIZING A CARBOHYDRATE CONTAINING EPITOPE ON CD-43 AND CEA EXPRESSED ON CANCER CELLS AND METHODS USING SAME
有权
识别包含在CD-43上的含有硫酸酯的抗体和在癌细胞上表达的CEA和使用其的方法
- 专利标题: ANTIBODIES RECOGNIZING A CARBOHYDRATE CONTAINING EPITOPE ON CD-43 AND CEA EXPRESSED ON CANCER CELLS AND METHODS USING SAME
- 专利标题(中): 识别包含在CD-43上的含有硫酸酯的抗体和在癌细胞上表达的CEA和使用其的方法
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申请号: US12338934申请日: 2008-12-18
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公开(公告)号: US20090191221A1公开(公告)日: 2009-07-30
- 发明人: Shih-Yao LIN , Leewen Lin , Yu-Ying Tsai
- 申请人: Shih-Yao LIN , Leewen Lin , Yu-Ying Tsai
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/18 ; C12N15/11 ; C12N15/00 ; C12N5/06 ; C12P21/08
摘要:
The present invention provides antibodies (such as chimeric and humanized antibodies) specifically bind to an epitope on CD43 and CEA expressed on nonhematopoietic cancer cells. In addition, the present invention also provides use of the antibodies described herein for diagnostic and therapeutic purposes.
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