One-piece heart prosthesis implantable in an anatomical position. According to the invention, the artificial left and right ventricles (2,8) have general directions (14, 15) arranged in an asymmetrical V shape, such that said ventricles approach each other as they move away from the means (6, 12) of connection to the natural left and right auricles, and the individual hydraulic actuators (7, 13), associated respectively with said artificial left and light ventricles (2, 8), are arranged near each other, in proximity to said artificial left ventricle (2).