发明申请
- 专利标题： MAGE-A3 PEPTIDES PRESENTED BY HLA-DR1 MOLECULES
- 专利标题（中）： 由HLA-DR1分子提供的MAGE-A3肽
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申请号： US12016690申请日： 2008-01-18
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公开(公告)号： US20090203124A1公开(公告)日： 2009-08-13
- 发明人: Yi Zhang , Pascal Chaux , Thierry Boon-Falleur , Pierre van der Bruggen
- 申请人： Yi Zhang , Pascal Chaux , Thierry Boon-Falleur , Pierre van der Bruggen
- 申请人地址： US NY New York
- 专利权人： Ludwig Institute for Cancer Research
- 当前专利权人： Ludwig Institute for Cancer Research
- 当前专利权人地址： US NY New York
- 主分类号： C12N5/00
- IPC分类号： C12N5/00 ; C07H21/04 ; C12N15/63
摘要：
The invention describes HLA class II binding peptides encoded by the MAGE tumor associated genes, as well as nucleic acids encoding such peptides and antibodies relating thereto. The peptides stimulate the activity and proliferation of CD4+ T lymphocytes. Methods and products also are provided for diagnosing and treating conditions characterized by expression of MAGE genes.
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