发明申请
- 专利标题: Thiazolones for Use as P13 Kinase Inhibitors
- 专利标题(中): 噻唑酮用作P13激酶抑制剂
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申请号: US12281188申请日: 2007-03-02
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公开(公告)号: US20090203732A1公开(公告)日: 2009-08-13
- 发明人: Dashyant Dhanak , Steven David Knight
- 申请人: Dashyant Dhanak , Steven David Knight
- 国际申请: PCT/US07/63120 WO 20070302
- 主分类号: A61K31/437
- IPC分类号: A61K31/437 ; A61P35/00 ; A61P9/00 ; A61P25/28 ; A61P11/06 ; A61P17/06 ; A61P19/02 ; A61P29/00 ; A61P1/00
摘要:
Invented is a method of inhibiting the activity/function of PI3 kinases using substituted thiazolones. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of substituted thiazolones.
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