发明申请
US20090203916A1 Amorphous object of cinnamide compound 失效
肉桂酰胺化合物的无定形物

  • 专利标题: Amorphous object of cinnamide compound
  • 专利标题(中): 肉桂酰胺化合物的无定形物
  • 申请号: US11663550
    申请日: 2005-10-25
  • 公开(公告)号: US20090203916A1
    公开(公告)日: 2009-08-13
  • 发明人: Ikuo KushidaEriko DoiKoichi Ito
  • 申请人: Ikuo KushidaEriko DoiKoichi Ito
  • 优先权: JP2004-310909 20041026
  • 国际申请: PCT/JP05/19626 WO 20051025
  • 主分类号: C07D401/10
  • IPC分类号: C07D401/10
Amorphous object of cinnamide compound
摘要:
An amorphous object of (3E)-1-[l(s)-1-(4-fluorophenyl)ethyl]-3-[3-methoxy-4-(4methyl-1H-imidazol-1-yl)benzylidene]piperidine-2-one, which is represented by the formula (1) and has Aβ-production inhibitory activity. The amorphous object has such satisfactory properties that it has excellent solubility, is stable, does not readily become a crystalline form, and has low hygroscopicity. It is hence suitable for use in pharmaceutical preparations.
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