发明申请
- 专利标题： Amorphous object of cinnamide compound
- 专利标题（中）： 肉桂酰胺化合物的无定形物
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申请号： US11663550申请日： 2005-10-25
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公开(公告)号： US20090203916A1公开(公告)日： 2009-08-13
- 发明人: Ikuo Kushida , Eriko Doi , Koichi Ito
- 申请人： Ikuo Kushida , Eriko Doi , Koichi Ito
- 优先权： JP2004-310909 20041026
- 国际申请： PCT/JP05/19626 WO 20051025
- 主分类号： C07D401/10
- IPC分类号： C07D401/10
摘要：
An amorphous object of (3E)-1-[l(s)-1-(4-fluorophenyl)ethyl]-3-[3-methoxy-4-(4methyl-1H-imidazol-1-yl)benzylidene]piperidine-2-one, which is represented by the formula (1) and has Aβ-production inhibitory activity. The amorphous object has such satisfactory properties that it has excellent solubility, is stable, does not readily become a crystalline form, and has low hygroscopicity. It is hence suitable for use in pharmaceutical preparations.
公开/授权文献
- US07923563B2 Amorphous object of cinnamide compound 公开/授权日：2011-04-12