发明申请
US20090208479A1 Compositions and Methods for Effecting the Levels of High Density Lipoprotein (HDL) Cholesterol and Apolipoprotein AI, Very Low Density Lipoprotein (VLDL) Cholesterol and Low Density Lipoprotein (LDL) Cholesterol
审中-公开
用于影响高密度脂蛋白（HDL）胆固醇和载脂蛋白AI，极低密度脂蛋白（VLDL）胆固醇和低密度脂蛋白（LDL）胆固醇水平的组合物和方法
- 专利标题： Compositions and Methods for Effecting the Levels of High Density Lipoprotein (HDL) Cholesterol and Apolipoprotein AI, Very Low Density Lipoprotein (VLDL) Cholesterol and Low Density Lipoprotein (LDL) Cholesterol
- 专利标题（中）： 用于影响高密度脂蛋白（HDL）胆固醇和载脂蛋白AI，极低密度脂蛋白（VLDL）胆固醇和低密度脂蛋白（LDL）胆固醇水平的组合物和方法
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申请号： US12197970申请日： 2008-08-25
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公开(公告)号： US20090208479A1公开(公告)日： 2009-08-20
- 发明人: Michael Jaye , Kim-Anh Thi Doan , John A. Krawiec , Kevin J. Lynch , Dilip V. Amin , Victoria J. South , Dawn Marchadier , Cyrille Maugeais , Daniel J. Rader
- 申请人： Michael Jaye , Kim-Anh Thi Doan , John A. Krawiec , Kevin J. Lynch , Dilip V. Amin , Victoria J. South , Dawn Marchadier , Cyrille Maugeais , Daniel J. Rader
- 主分类号： A61K38/46
- IPC分类号： A61K38/46 ; C12Q1/60
摘要：
Compositions and methods for raising the level of HDL cholesterol and apolipoprotein AI in a patient and for lowering the levels of VLDL cholesterol and LDL cholesterol in a patient, including compositions and methods which effect the expression of a gene, LIPG, which encodes a lipase enzyme that is a member of the triacylglycerol lipase family or which effect the enzymatic activity of the enzyme.
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