Invention Application
US20090208575A1 Pharmaceutical Composition Of Acid Labile Substances 审中-公开
酸不稳定物质的药物组成

Pharmaceutical Composition Of Acid Labile Substances
Abstract:
A pharmaceutical composition for oral use comprising a) a core comprising an effective amount of benzimidazole and an organic stabilizing agent which is present in an amount effective to stabilize the composition, b) an intermediate layer comprising of a water insoluble polymer and an organic stabilizer, and c) an outer enteric coating layer. The organic stabilizing agent is present in the core from about 1% to about 10% by weight of the core and in the intermediate layer from about 5% to about 35% by weight of intermediate layer.
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