发明申请
- 专利标题: Methods for Treatment of Sexual Dysfunction
- 专利标题(中): 治疗性功能障碍的方法
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申请号: US11922128申请日: 2006-06-13
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公开(公告)号: US20090221553A1公开(公告)日: 2009-09-03
- 发明人: Joseph Palumbo , Jonathan Sporn , Thomas Steckler , Yong Moon Choi , James S. Lee
- 申请人: Joseph Palumbo , Jonathan Sporn , Thomas Steckler , Yong Moon Choi , James S. Lee
- 国际申请: PCT/US2006/023068 WO 20060613
- 主分类号: A61K31/553
- IPC分类号: A61K31/553 ; A61K31/27 ; A61K31/55 ; A61P15/00
摘要:
This invention is directed to a method of treating sexual dysfunction in a subject, comprising the step of administering a therapeutically effective amount of a compound of Formula (I): or a pharmaceutically acceptable salt or ester thereof wherein Rx is a member selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, halogen selected from F, CI, Br and I, alkoxy containing 1 to 3 carbon atoms, nitro, hydroxy, trifluoromethyl, and thioalkoxy containing 1 to 3 carbon atoms; x is an integer of 1 to 3, with the proviso that R may be the same or different when x is 2 or 3; R1 and R2 can be the same or different from each other and are independently selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, aryl, arylalkyl, cycloalkyl of 3 to 7 carbon atoms; R1 and R2 can be joined to form a 5 to 7-membered heterocycle substituted with a member selected from the group consisting of hydrogen, alkyl, and aryl groups, wherein the cyclic compound can comprise 1 to 2 nitrogen atoms and O to 1 oxygen atom, wherein the nitrogen atoms are not directly connected with each other or with the oxygen atom.
公开/授权文献
- US08552060B2 Methods for treatment of sexual dysfunction 公开/授权日:2013-10-08
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