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公开(公告)号：US20090221553A1
公开(公告)日：2009-09-03
申请号：US11922128
申请日：2006-06-13
IPC分类号： A61K31/553 , A61K31/27 , A61K31/55 , A61P15/00
CPC分类号： A61K31/165
摘要： This invention is directed to a method of treating sexual dysfunction in a subject, comprising the step of administering a therapeutically effective amount of a compound of Formula (I): or a pharmaceutically acceptable salt or ester thereof wherein Rx is a member selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, halogen selected from F, CI, Br and I, alkoxy containing 1 to 3 carbon atoms, nitro, hydroxy, trifluoromethyl, and thioalkoxy containing 1 to 3 carbon atoms; x is an integer of 1 to 3, with the proviso that R may be the same or different when x is 2 or 3; R1 and R2 can be the same or different from each other and are independently selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, aryl, arylalkyl, cycloalkyl of 3 to 7 carbon atoms; R1 and R2 can be joined to form a 5 to 7-membered heterocycle substituted with a member selected from the group consisting of hydrogen, alkyl, and aryl groups, wherein the cyclic compound can comprise 1 to 2 nitrogen atoms and O to 1 oxygen atom, wherein the nitrogen atoms are not directly connected with each other or with the oxygen atom.
摘要翻译： 本发明涉及治疗受试者的性功能障碍的方法，其包括施用治疗有效量的式（I）化合物或其药学上可接受的盐或酯的步骤，其中Rx是选自下组的成员 由氢，1至8个碳原子的低级烷基，选自F，Cl，Br和I的卤素，含有1至3个碳原子的烷氧基，硝基，羟基，三氟甲基和含有1至3个碳原子的硫代烷氧基组成; x为1〜3的整数，条件是当x为2或3时R可以相同或不同; R 1和R 2可以相同或不同，并且独立地选自氢，1至8个碳原子的低级烷基，芳基，芳基烷基，3至7个碳原子的环烷基; R1和R2可以连接形成被选自氢，烷基和芳基的成员所取代的5至7元杂环，其中环状化合物可包含1至2个氮原子和0至1个氧原子 其中氮原子彼此不直接连接或与氧原子直接连接。
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公开(公告)号：US08552060B2
公开(公告)日：2013-10-08
申请号：US11922128
申请日：2006-06-13
申请人： Joseph Palumbo , Jonathan Sporn , Thomas Steckler , Yong Choi , James S. Lee
发明人： Joseph Palumbo , Jonathan Sporn , Thomas Steckler , Yong Choi , James S. Lee
IPC分类号： A61K31/24
CPC分类号： A61K31/165
摘要： This invention is directed to a method of treating sexual dysfunction in a subject, comprising the step of administering a therapeutically effective amount of a compound of Formula (I): or a pharmaceutically acceptable salt or ester thereof wherein Rx is a member selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, halogen selected from F, CI, Br and I, alkoxy containing 1 to 3 carbon atoms, nitro, hydroxy, trifluoromethyl, and thioalkoxy containing 1 to 3 carbon atoms; x is an integer of 1 to 3, with the proviso that R may be the same or different when x is 2 or 3; R1 and R2 can be the same or different from each other and are independently selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, aryl, arylalkyl, cycloalkyl of 3 to 7 carbon atoms; R1 and R2 can be joined to form a 5 to 7-membered heterocycle substituted with a member selected from the group consisting of hydrogen, alkyl, and aryl groups, wherein the cyclic compound can comprise 1 to 2 nitrogen atoms and O to 1 oxygen atom, wherein the nitrogen atoms are not directly connected with each other or with the oxygen atom.
摘要翻译： 本发明涉及治疗受试者的性功能障碍的方法，其包括施用治疗有效量的式（I）化合物或其药学上可接受的盐或酯的步骤，其中Rx是选自下组的成员 由氢，1至8个碳原子的低级烷基，选自F，Cl，Br和I的卤素，含有1至3个碳原子的烷氧基，硝基，羟基，三氟甲基和含有1至3个碳原子的硫代烷氧基组成; x为1〜3的整数，条件是当x为2或3时R可以相同或不同; R 1和R 2可以相同或不同，并且独立地选自氢，1至8个碳原子的低级烷基，芳基，芳基烷基，3至7个碳原子的环烷基; R1和R2可以连接形成被选自氢，烷基和芳基的成员所取代的5至7元杂环，其中环状化合物可包含1至2个氮原子和0至1个氧原子 其中氮原子彼此不直接连接或与氧原子直接连接。
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公开(公告)号：USD413254S
公开(公告)日：1999-08-31
申请号：US69337
申请日：1997-03-31
申请人： James S. Lee
设计人： James S. Lee
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公开(公告)号：US3981837A
公开(公告)日：1976-09-21
申请号：US453924
申请日：1974-03-22
申请人： John G. Papalos , James S. Lee
发明人： John G. Papalos , James S. Lee
CPC分类号： C08F2/26
摘要： Large particle size synthetic latexes are produced by incorporating novel emulsifiers into the polymerization recipes. These bio-degradable emulsifiers are salts of partially mono-sulfonated mono-alkyl benzenes.
摘要翻译： 通过在聚合配方中引入新的乳化剂来生产大粒径的合成胶乳。 这些生物可降解乳化剂是部分单磺化单烷基苯的盐。
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公开(公告)号：US09376835B2
公开(公告)日：2016-06-28
申请号：US14449450
申请日：2014-08-01
CPC分类号： E05B17/06 , E05B47/0038
摘要： A magnetically mounted template for identifying the optimum installation location for a door hardware device. The template has a working element that engages a cooperating door hardware device, for example, a working latch that engages a bolt. The template is particularly suitable for installing electrically operable door hardware devices, such as electric strikes, which require wiring as well as mechanical attachment to a door frame or door.
摘要翻译： 用于识别门硬件设备的最佳安装位置的磁性安装模板。 模板具有与协作的门硬件装置（例如，与螺栓接合的工作闩锁）接合的工作元件。 该模板特别适用于安装电动可操作的门硬件设备，例如电击，其需要布线以及机械附接到门框或门。
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公开(公告)号：US09115758B2
公开(公告)日：2015-08-25
申请号：US13478078
申请日：2012-05-22
申请人： Troy M. Herndon , James S. Lee , Jeffry A. Leblanc , Robert A. Nottingham , Norbert S. Parsoneault , Thaveesinn Vasavakul , James S. Bowdoin , Christopher M. Woldemar , Jerry J. Weingord
发明人： Troy M. Herndon , James S. Lee , Jeffry A. Leblanc , Robert A. Nottingham , Norbert S. Parsoneault , Thaveesinn Vasavakul , James S. Bowdoin , Christopher M. Woldemar , Jerry J. Weingord
CPC分类号： F16C33/103 , F16C17/107 , F16C33/745 , F16C41/008 , F16C2370/12 , H02K5/1677 , Y10T29/49009 , Y10T29/49639 , Y10T29/49702 , Y10T29/49703 , Y10T29/53443
摘要： In one example, an FDB motor having a shield member is provided. In one example, the method includes disposing a first member and a second member for relative rotation about an axis of rotation. An annular shield member is attached to the first member, the shield member disposed adjacent a fluid reservoir for containing a bearing fluid. The reservoir is filled through an aperture (e.g., a fill hole) in the shield member. Thereafter, the aperture is at least partially sealed. The aperture may be hermetically sealed via one or more laser pulses. In other examples, a two piece shield is provided for shielding a reservoir without a fill hole.
摘要翻译： 在一个示例中，提供具有屏蔽构件的FDB电动机。 在一个示例中，该方法包括布置围绕旋转轴线相对旋转的第一构件和第二构件。 环形屏蔽构件附接到第一构件，屏蔽构件邻近流体储存器设置以容纳轴承流体。 储存器通过屏蔽构件中的孔（例如，填充孔）填充。 此后，孔径至少部分地被密封。 孔可以通过一个或多个激光脉冲气密密封。 在其他示例中，提供了一个用于屏蔽储存器而没有填充孔的双件式屏蔽件。
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公开(公告)号：US08181348B2
公开(公告)日：2012-05-22
申请号：US11097050
申请日：2005-04-01
申请人： Troy M. Herndon , James S. Lee , Jeffry A. Leblanc , Robert A. Nottingham , Norbert S. Parsoneault , Thaveesinn Vasavakul , James S. Bowdoin , Christopher M. Woldemar , Jerry J. Weingord
发明人： Troy M. Herndon , James S. Lee , Jeffry A. Leblanc , Robert A. Nottingham , Norbert S. Parsoneault , Thaveesinn Vasavakul , James S. Bowdoin , Christopher M. Woldemar , Jerry J. Weingord
CPC分类号： F16C33/103 , F16C17/107 , F16C33/745 , F16C41/008 , F16C2370/12 , H02K5/1677 , Y10T29/49009 , Y10T29/49639 , Y10T29/49702 , Y10T29/49703 , Y10T29/53443
摘要： In one example, a fluid dynamic bearing motor having a shield member is provided. In one example, the method includes disposing a first member and a second member for relative rotation about an axis of rotation. An annular shield member is attached to the first member, the shield member disposed adjacent a fluid reservoir for containing a bearing fluid. The reservoir is filled through an aperture (e.g., a fill hole) in the shield member. Thereafter, the aperture is at least partially sealed. The aperture may be hermetically sealed via one or more laser pulses. In other examples, a two piece shield is provided for shielding a reservoir without a fill hole.
摘要翻译： 在一个示例中，提供了具有屏蔽构件的流体动力轴承马达。 在一个示例中，该方法包括布置围绕旋转轴线相对旋转的第一构件和第二构件。 环形屏蔽构件附接到第一构件，屏蔽构件邻近流体储存器设置以容纳轴承流体。 储存器通过屏蔽构件中的孔（例如，填充孔）填充。 此后，孔径至少部分地被密封。 孔可以通过一个或多个激光脉冲气密密封。 在其他示例中，提供了一个用于屏蔽储存器而没有填充孔的双件式屏蔽件。
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公开(公告)号：US5598753A
公开(公告)日：1997-02-04
申请号：US384922
申请日：1995-02-07
申请人： James S. Lee
发明人： James S. Lee
CPC分类号： F16B23/0007 , B25B13/485 , F16B23/0076 , Y10S411/911
摘要： An eagle wing tips tamper-proof fastener and driver tool with complementary driver head contact for operating the same. A conventional threaded shank is perpendicularly connected to a substantially flat head. The head comprises a plurality of recessed channels numbering three and the channels radially curve outwards from a common center point. In one embodiment, the substantially vertical right and left walls of each channel allow application of torque with the driver tool in both directions. In an alternate embodiment, the substantially vertical right wall and the surface of the substantially inclined left wall allow application of torque with the driver tool to the right only.
摘要翻译： 鹰翼提示防篡改紧固件和驱动器工具，具有互补的驱动头接触，用于操作。 常规的螺纹杆垂直地连接到基本平坦的头部。 头部包括多个凹槽，编号为三个，并且通道从公共中心点向外径向弯曲。 在一个实施例中，每个通道的大致垂直的左右壁允许在两个方向上与驱动器工具施加扭矩。 在替代实施例中，基本上垂直的右壁和基本上倾斜的左壁的表面允许仅将驾驶工具施加扭矩。
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公开(公告)号：US20150113817A1
公开(公告)日：2015-04-30
申请号：US14449450
申请日：2014-08-01
IPC分类号： E05B17/06
CPC分类号： E05B17/06 , E05B47/0038
摘要： A magnetically mounted template for identifying the optimum installation location for a door hardware device. The template has a working element that engages a cooperating door hardware device, for example, a working latch that engages a bolt. The template is particularly suitable for installing electrically operable door hardware devices, such as electric strikes, which require wiring as well as mechanical attachment to a door frame or door.
摘要翻译： 用于识别门硬件设备的最佳安装位置的磁性安装模板。 模板具有与协作的门硬件装置（例如，与螺栓接合的工作闩锁）接合的工作元件。 该模板特别适用于安装电动可操作的门硬件设备，例如电击，其需要布线以及机械附接到门框或门。
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公开(公告)号：US20120319516A1
公开(公告)日：2012-12-20
申请号：US13478078
申请日：2012-05-22
申请人： Troy M. Herndon , James S. Lee , Jeffry A. Leblanc , Robert A. Nottingham , Norbert S. Parsoneault , Thaveesinn Vasavakul , James S. Bowdoin , Christopher M. Woldemar , Jerry J. Weingord
发明人： Troy M. Herndon , James S. Lee , Jeffry A. Leblanc , Robert A. Nottingham , Norbert S. Parsoneault , Thaveesinn Vasavakul , James S. Bowdoin , Christopher M. Woldemar , Jerry J. Weingord
IPC分类号： H02K5/16
CPC分类号： F16C33/103 , F16C17/107 , F16C33/745 , F16C41/008 , F16C2370/12 , H02K5/1677 , Y10T29/49009 , Y10T29/49639 , Y10T29/49702 , Y10T29/49703 , Y10T29/53443
摘要： In one example, an FDB motor having a shield member is provided. In one example, the method includes disposing a first member and a second member for relative rotation about an axis of rotation. An annular shield member is attached to the first member, the shield member disposed adjacent a fluid reservoir for containing a bearing fluid. The reservoir is filled through an aperture (e.g., a fill hole) in the shield member. Thereafter, the aperture is at least partially sealed. The aperture may be hermetically sealed via one or more laser pulses. In other examples, a two piece shield is provided for shielding a reservoir without a fill hole.
摘要翻译： 在一个示例中，提供具有屏蔽构件的FDB电动机。 在一个示例中，该方法包括布置围绕旋转轴线相对旋转的第一构件和第二构件。 环形屏蔽构件附接到第一构件，屏蔽构件邻近流体储存器设置以容纳轴承流体。 储存器通过屏蔽构件中的孔（例如，填充孔）填充。 此后，孔径至少部分地被密封。 孔可以通过一个或多个激光脉冲气密密封。 在其他示例中，提供了一个用于屏蔽储存器而没有填充孔的双件式屏蔽件。
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