发明申请
US20090227587A1 Pyrimidines as inhibitors of phosphoinositide-3-kinases (PI3K)
审中-公开
嘧啶类作为磷酸肌醇-3-激酶（PI3K）的抑制剂
- 专利标题： Pyrimidines as inhibitors of phosphoinositide-3-kinases (PI3K)
- 专利标题（中）： 嘧啶类作为磷酸肌醇-3-激酶（PI3K）的抑制剂
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申请号： US11664975申请日： 2004-10-19
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公开(公告)号： US20090227587A1公开(公告)日： 2009-09-10
- 发明人: Michael Kevin Connolly , Rocco Dean Gogliotti , Mark Stephen Plummer , Melean Visnick
- 申请人： Michael Kevin Connolly , Rocco Dean Gogliotti , Mark Stephen Plummer , Melean Visnick
- 专利权人： Warner-Lambert Company LLC
- 当前专利权人： Warner-Lambert Company LLC
- 国际申请： PCT/IB04/03417 WO 20041019
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D413/14
摘要：
The present invention provides pyrimidines of Formula I: wherein R4, R6, and Y have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cardiovascular diseases, and cancers. Also provided are pharmaceutical compositions comprising one or more compounds of Formula I.
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