发明申请
- 专利标题： Inhibitors of checkpoint kinases
- 专利标题（中）： 检测点激酶抑制剂
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申请号： US11921598申请日： 2006-06-05
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公开(公告)号： US20090233896A1公开(公告)日： 2009-09-17
- 发明人: Kenneth L. Arrington , Vadim Y. Dudkin , Mark E. Fraley , Jacob M. Hoffman , Constantine Kreatsoulas , Cheng Wang
- 申请人： Kenneth L. Arrington , Vadim Y. Dudkin , Mark E. Fraley , Jacob M. Hoffman , Constantine Kreatsoulas , Cheng Wang
- 国际申请： PCT/US2006/021846 WO 20060605
- 主分类号： A61K31/397
- IPC分类号： A61K31/397 ; C07D413/14 ; A61K31/5377 ; C07D401/14 ; A61K31/506 ; C07D403/00 ; A61K31/496 ; A61P35/00
摘要：
The instant invention provides for compounds which comprise substituted pyridyl aminothiazoles that inhibit CHK1 activity. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting CHK1 activity by administering the compound to a patient in need of treatment of cancer.
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