发明申请
- 专利标题： Crystalline forms of mc4r agonist and process for synthesis
- 专利标题（中）： mc4r激动剂的结晶形式和合成方法
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申请号： US11921824申请日： 2006-06-23
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公开(公告)号： US20090233967A1公开(公告)日： 2009-09-17
- 发明人: Ralph Calabria , Yu Cheng , Russell R. Ferlita , Ashkan Kamali , Jerry A. Murry , David Mathre , Andrey V. Peresypkin , Karen Thompson , Jian Wang , Robert M. Wenslow
- 申请人： Ralph Calabria , Yu Cheng , Russell R. Ferlita , Ashkan Kamali , Jerry A. Murry , David Mathre , Andrey V. Peresypkin , Karen Thompson , Jian Wang , Robert M. Wenslow
- 国际申请： PCT/US2006/024573 WO 20060623
- 主分类号： A61K31/454
- IPC分类号： A61K31/454 ; C07D401/06
摘要：
The present invention relates to a process for producing N-{(1S)-1-[2-(1-{[(3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl]carbonyl}piperidin-4-yl)-5-chlorophenyl]ethyl}acetamide, and novel crystalline salts, hydrates, solvates, and polymorphic forms thereof.
公开/授权文献
- US08129413B2 Crystalline forms of MC4R agonist and process for synthesis 公开/授权日：2012-03-06
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