发明申请
- 专利标题: COMPOSITION FOR NUCLEIC-ACID TRANSFECTION
- 专利标题(中): 用于核酸转运的组合物
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申请号: US12306620申请日: 2007-06-29
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公开(公告)号: US20090239222A1公开(公告)日: 2009-09-24
- 发明人: Hiroshi Kikuchi , Hideo Kobayashi , Kouichi Hashimoto , Ayako Iijima , Daigo Asano
- 申请人: Hiroshi Kikuchi , Hideo Kobayashi , Kouichi Hashimoto , Ayako Iijima , Daigo Asano
- 优先权: JP2006-182510 20060630
- 国际申请: PCT/JP07/00720 WO 20070629
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C07C233/00
摘要:
To provide a nucleic-acid-transfecting composition which exhibits low cytotoxicity, which facilitates a nucleic acid transfection into cells, and which improves expression of the nucleic acid in the cells.The invention provides a composition for transfecting a nucleic acid into a cell, including a compound represented by the following formula (I) (wherein each of R1 and R2, which are identical to or different from each other, represents a saturated or unsaturated hydrocarbon group; R3 represents a C1-6 alkyl group or a C1-6 hydroxyalkyl group; m is an integer from 1 to 10; and X represents a halogen atom), and a phospholipid.
公开/授权文献
- US08227248B2 Composition for nucleic-acid transfection 公开/授权日:2012-07-24
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