发明申请
US20090239890A1 SPIRO SUBSTITUTED CYCLOPROPANE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
审中-公开
SPIRO替代环孢素化合物治疗炎症性疾病
- 专利标题： SPIRO SUBSTITUTED CYCLOPROPANE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
- 专利标题（中）： SPIRO替代环孢素化合物治疗炎症性疾病
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申请号： US12388984申请日： 2009-02-19
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公开(公告)号： US20090239890A1公开(公告)日： 2009-09-24
- 发明人: Joseph A. Kozlowski , Shing-Chun Wong , Neng-Yang Shih , Zhuyan Guo
- 申请人： Joseph A. Kozlowski , Shing-Chun Wong , Neng-Yang Shih , Zhuyan Guo
- 专利权人： Schering Corporation
- 当前专利权人： Schering Corporation
- 主分类号： A61K31/4709
- IPC分类号： A61K31/4709 ; C07D401/12 ; A61P25/00
摘要：
A compound of the Formula I: or a pharmaceutically acceptable salt, solvate or isomer thereof, can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-α or combinations thereof.
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