发明申请
- 专利标题： METHOD AND APPARATUS FOR DETERMINING CHEMOSENSITIVITY
- 专利标题（中）： 用于确定化学敏感性的方法和装置
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申请号： US12407301申请日： 2009-03-19
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公开(公告)号： US20090246787A1公开(公告)日： 2009-10-01
- 发明人: Tomoko Oyama , Tomokazu Yoshida , Satoshi Nakayama , Yumi Takinowaki
- 申请人： Tomoko Oyama , Tomokazu Yoshida , Satoshi Nakayama , Yumi Takinowaki
- 申请人地址： JP Kobe-shi
- 专利权人： SYSMEX CORPORATION
- 当前专利权人： SYSMEX CORPORATION
- 当前专利权人地址： JP Kobe-shi
- 优先权： JP2008-091443 20080331
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12Q1/02 ; C12M1/00
摘要：
A method for determining chemosensitivity of a malignant tumor cell to anthracycline is described herein. According to this method, first tumor cell and second tumor sell are first prepared. The first tumor cell is not treated with anthracycline, and on the other the second tumor cell is treated with anthracycline. Secondly, first and second activity levels of CDK1 are measured. The first activity level is activity of CDK1 in the first tumor cell and the second activity level is that of CDK1 in the second tumor cell. Finally, chemosensitivity of the malignant tumor cell is determined. The determination is based on the first and second activity levels.