发明申请
- 专利标题： Combination Therapy to Treat Hepatitis B Virus
- 专利标题（中）： 联合治疗乙型肝炎病毒
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申请号： US12483800申请日： 2009-06-12
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公开(公告)号： US20090247487A1公开(公告)日： 2009-10-01
- 发明人: Phillip A. Furman , George R. Painter, III , David W. Barry , Franck Rousseau
- 申请人： Phillip A. Furman , George R. Painter, III , David W. Barry , Franck Rousseau
- 申请人地址： US CA Foster City
- 专利权人： GILEAD SCIENCES, INC.
- 当前专利权人： GILEAD SCIENCES, INC.
- 当前专利权人地址： US CA Foster City
- 主分类号： A61K31/675
- IPC分类号： A61K31/675 ; A61K31/506 ; A61K31/52
摘要：
The present invention is directed to a method for treating hepatitis B virus infection in humans comprising administering a synergistically effective amount of agents having known anti-hepatitis B virus activity in combination or alternation. Specifically, the invention is directed to a method for treating hepatitis B virus infection comprising administering FTC in combination or alternation with penciclovir, famciclovir or Bis-POM-PMEA. Additionally, the invention is directed to a method for treating hepatitis B virus infection comprising administering L-FMAU in combination or alternation with DAPD, penciclovir or Bis-POM-PMEA. The invention is further directed to a method for treating hepatitis B virus infection comprising administering DAPD in combination or alternation with Bis-POM-PMEA.
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