Invention Application
- Patent Title: TRISUBSTITUTED 1,2,4-TRIAZOLES
- Patent Title (中): 分离的1,2,4-TRIAZOLES
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Application No.: US12297059Application Date: 2007-04-19
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Publication No.: US20090253691A1Publication Date: 2009-10-08
- Inventor: Johannes Wilhelmus John F. Thuring , Gregor James MacDonald , Anne Simone Josephine Lesage , Wei Zhuang , Marcel Frans Leopold De Bruyn , Frans Alfons Maria Van Den Keybus , Yves Emiel Maria Van Roosbroeck , Theodorus Dinklo
- Applicant: Johannes Wilhelmus John F. Thuring , Gregor James MacDonald , Anne Simone Josephine Lesage , Wei Zhuang , Marcel Frans Leopold De Bruyn , Frans Alfons Maria Van Den Keybus , Yves Emiel Maria Van Roosbroeck , Theodorus Dinklo
- Applicant Address: BE Beerse GB Essex
- Assignee: JANSSEN PHARMACEUTICA N.V.,BIOFOCUS DPI LIMITED
- Current Assignee: JANSSEN PHARMACEUTICA N.V.,BIOFOCUS DPI LIMITED
- Current Assignee Address: BE Beerse GB Essex
- Priority: EP06112754.4 20060419
- International Application: PCT/EP2007/053829 WO 20070419
- Main IPC: A61K31/538
- IPC: A61K31/538 ; C07D407/10 ; A61K31/4196 ; A61K31/4439 ; C07D401/04 ; C07D491/048 ; A61K31/4355 ; C07D413/10
Abstract:
The present invention relates to 3-aniline-5-aryl triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I). The invention particularly relates to positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulator having the capability to increase the efficacy of nicotinic receptor agonists.
Public/Granted literature
- US08143419B2 Trisubstituted 1,2,4-triazoles Public/Granted day:2012-03-27
Information query
IPC分类:
