发明申请
- 专利标题： AZAINDOLE DERIVATIVES AS CFTR MODULATORS
- 专利标题（中）： 亚胺衍生物作为CFTR调节剂
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申请号： US12422496申请日： 2009-04-13
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公开(公告)号： US20090253736A1公开(公告)日： 2009-10-08
- 发明人: Sara Hadida-Ruah , Jinglan Zhou , Mark Miller , Brian Bear
- 申请人： Sara Hadida-Ruah , Jinglan Zhou , Mark Miller , Brian Bear
- 申请人地址： US MA Cambridge
- 专利权人： VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人： VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人地址： US MA Cambridge
- 主分类号： A61K31/437
- IPC分类号： A61K31/437 ; C07D471/04 ; C12N5/00 ; G01N33/566 ; C07D405/14 ; A61P7/00 ; A61P11/00 ; A61P35/00 ; A61P25/28 ; A61P25/16 ; A61P5/00
摘要：
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
公开/授权文献
- US08563573B2 Azaindole derivatives as CFTR modulators 公开/授权日：2013-10-22
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