发明申请
- 专利标题： Substance Specific to Human PD-1
- 专利标题（中）： 人类PD-1特异性物质
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申请号： US12469188申请日： 2009-05-20
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公开(公告)号： US20090263865A1公开(公告)日： 2009-10-22
- 发明人: Tasuku HONJO , Shiro Shibayama , Kazuhiko Takeda , Masayoshi Matsuo , Takao Yoshida , Masakazu Miyamoto
- 申请人： Tasuku HONJO , Shiro Shibayama , Kazuhiko Takeda , Masayoshi Matsuo , Takao Yoshida , Masakazu Miyamoto
- 申请人地址： JP Kyoto-shi JP Osaka-shi
- 专利权人： Tasuku HONJO,ONO PHARMACEUTICAL CO., LTD.
- 当前专利权人： Tasuku HONJO,ONO PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： JP Kyoto-shi JP Osaka-shi
- 优先权： JP2003-14793 20030123
- 主分类号： C12P21/02
- IPC分类号： C12P21/02 ; C07K16/46 ; C07H21/00 ; C07H21/04 ; C12N15/63 ; C12N5/10 ; A61K39/395
摘要：
The present invention relates to a substance specific to human PD-1 comprising a part that recognizes human PD-1, a part that recognizes a membrane protein in cell membrane of human PD-1-expressing cells, and linkers. Since the substance specific to human PD-1 selectively can recognize human PD-1 and a membrane protein on cell membrane of human PD-1-expressing cells and can transmit inhibitory signal of human PD-1, it is useful for therapy and/or prevention of diseases caused by immunopathy.
公开/授权文献
- US07998479B2 Substance specific to human PD-1 公开/授权日：2011-08-16
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