发明申请
- 专利标题: METHOD OF DIAGNOSING GUM DISEASE-WOUND HEALING USING SINGLE NUCLEOTIDE POLYMORPHISM PROFILES
- 专利标题(中): 使用单核多核型多态性诊断糖尿病治疗方法
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申请号: US11817339申请日: 2006-03-10
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公开(公告)号: US20090264507A1公开(公告)日: 2009-10-22
- 发明人: Ichiro Nishimura , Audrey Lin , Neal Garret
- 申请人: Ichiro Nishimura , Audrey Lin , Neal Garret
- 申请人地址: US CA Oakland
- 专利权人: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- 当前专利权人: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- 当前专利权人地址: US CA Oakland
- 国际申请: PCT/US06/08678 WO 20060310
- 主分类号: A61K31/7088
- IPC分类号: A61K31/7088 ; C12Q1/68 ; C07H21/04 ; C07K16/18 ; A61P1/02
摘要:
The present invention provides methods for diagnosing and providing a prognosis for wound healing in a patient by characterizing and analyzing the single nucleotide polymorphism (SNP) of a wound healing associated gene wit3.0. In particular, the invention provides a method of diagnosis and prognosis of oral disease-wound healing, including gingival periodontitis and residual alveolar bone resorption, by characterizing and analyzing the wound inducible transcript-3.0 (wit3.0)SNP pattern in a sample of a patient with and without susceptibility for the disease.
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