发明申请
- 专利标题: Controlled Release Solid Preparation
- 专利标题(中): 控释固体制剂
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申请号: US12084824申请日: 2006-11-10
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公开(公告)号: US20090269401A1公开(公告)日: 2009-10-29
- 发明人: Masaaki Endo , Kazuhiro Obae , Ichirou Ibuki , Yoshihito Yaginuma
- 申请人: Masaaki Endo , Kazuhiro Obae , Ichirou Ibuki , Yoshihito Yaginuma
- 优先权: JP2005-327490 20051111
- 国际申请: PCT/JP2006/322487 WO 20061110
- 主分类号: A61K47/26
- IPC分类号: A61K47/26 ; A61K9/20
摘要:
Disclosed is a solid preparation which comprises at least one active ingredient and at least one dissolution-controlling base substance and can be formed by compression molding, wherein the dissolution-controlling base substance contains 5.0 to 99.9% by weight (inclusive) of a modified starch having a moisture retaining capacity of 400% or more and a gel indentation load of 200 g or more, containing a water-soluble ingredient in an amount of 40 to 95% by weight, having particles passing through a 75 μm-mesh sieve in the proportion of 90% by weight or more and particles passing through a 32 μm-mesh sieve in the proportion of 20% by weight or more, and having an average particle diameter of not smaller than 20 μm and smaller than 50 μm.
公开/授权文献
- US09029427B2 Controlled release solid preparation 公开/授权日:2015-05-12
信息查询
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