发明申请
US20090270432A1 7-[2-[4-(6-FLUORO-3-METHYL-1,2-BENZISOXAZOL-5-YL)-1-PIPERAZINYL]ETHYL]-2-(1-PROPYNYL)-7H-PYRAZOLO-[4,3-e]-[1,2,4]-TRIAZOLO-[1,5-c]-PYRIMIDIN-5-AMINE
有权
7- [2- [4-(6-氟-3-甲基-1,2苯并恶唑-5-基)-1-哌嗪基]乙基] -2-(1-丙炔基)-7H-吡唑并[4, 3-e] - [1,2,4] - 三唑并[1,5-c] - 嘧啶-5-胺
- 专利标题: 7-[2-[4-(6-FLUORO-3-METHYL-1,2-BENZISOXAZOL-5-YL)-1-PIPERAZINYL]ETHYL]-2-(1-PROPYNYL)-7H-PYRAZOLO-[4,3-e]-[1,2,4]-TRIAZOLO-[1,5-c]-PYRIMIDIN-5-AMINE
- 专利标题(中): 7- [2- [4-(6-氟-3-甲基-1,2苯并恶唑-5-基)-1-哌嗪基]乙基] -2-(1-丙炔基)-7H-吡唑并[4, 3-e] - [1,2,4] - 三唑并[1,5-c] - 嘧啶-5-胺
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申请号: US12498013申请日: 2009-07-06
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公开(公告)号: US20090270432A1公开(公告)日: 2009-10-29
- 发明人: Craig D. Boyle , Samuel Chackalamannil , Unmesh Shah , Jean E. Lachowicz
- 申请人: Craig D. Boyle , Samuel Chackalamannil , Unmesh Shah , Jean E. Lachowicz
- 专利权人: Schering Corporation
- 当前专利权人: Schering Corporation
- 主分类号: A61K31/519
- IPC分类号: A61K31/519 ; C07D471/14 ; A61P25/16
摘要:
The compound having the structural formula I or a pharmaceutically acceptable salt thereof, is disclosed, as well as its use in the treatment of central nervous system diseases, in particular Parkinson's disease, Extra Pyramidal Syndrome, restless legs syndrome and attention deficit hyperactivity disorder, pharmaceutical compositions comprising it, and combinations with other agents.
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