发明申请
- 专利标题: RESORBABLE CERAMICS WITH CONTROLLED STRENGTH LOSS RATES
- 专利标题(中): 具有控制强度损失率的可再生陶瓷
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申请号: US12298012申请日: 2007-04-25
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公开(公告)号: US20090276056A1公开(公告)日: 2009-11-05
- 发明人: Susmita Bose , Amit Bandyopadhyay
- 申请人: Susmita Bose , Amit Bandyopadhyay
- 申请人地址: US WA Pullman
- 专利权人: WASHINGTON STATE UNIVERSITY
- 当前专利权人: WASHINGTON STATE UNIVERSITY
- 当前专利权人地址: US WA Pullman
- 国际申请: PCT/US2007/067444 WO 20070425
- 主分类号: A61F2/02
- IPC分类号: A61F2/02 ; A61L27/58 ; C04B35/03
摘要:
Particular aspects provide bioresorbable and biocompatible compositions for bioengineering, restoring or regenerating tissue or bone, comprising a three-dimensional porous or non-porous scaffold material comprising a calcium phosphate-based ceramic having at least one dopant therein selected from metal ion or ion dopants and metal oxide dopants, wherein the composition is sufficiently biocompatible to provide for a cell or tissue scaffold, and resorbable at a controlled resorption rate for controlled stregthloss, depending on dopant composition, under body, body fluid or simulated body fluid conditions. Preferably, the at least one dopant is selected from the group consisting of Zn2+, Mg2+, Si2+, Na+, K+, Sr2+, Cu2+, Fe3+/Fe2+, Ag+, Ti4+, CO32−, F−, MgO, ZnO, NaF, KF, FeO/Fe2O3, SrO, CuO, SiO2, TiO2, Ag2O and CaCO3, present in an amount between 0 and about 10 w %, from about 0.5 to about 5 w %, or from about 1 to about 3 w %, and methods of using same.
公开/授权文献
- US09028871B2 Resorbable ceramics with controlled strength loss rates 公开/授权日:2015-05-12