Invention Application
US20090281050A1 ANTI-BACTERIAL ACTIVITY OF 9-HYDROXY DERIVATIVES OF 6,11-BICYCLOLIDES
有权
6,11-双酚的9-羟基衍生物的抗细菌活性
- Patent Title: ANTI-BACTERIAL ACTIVITY OF 9-HYDROXY DERIVATIVES OF 6,11-BICYCLOLIDES
- Patent Title (中): 6,11-双酚的9-羟基衍生物的抗细菌活性
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Application No.: US12437616Application Date: 2009-05-08
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Publication No.: US20090281050A1Publication Date: 2009-11-12
- Inventor: Rajesh Iyengar , Yanchun Wang , Ly Tam Phan , Yat Sun Or
- Applicant: Rajesh Iyengar , Yanchun Wang , Ly Tam Phan , Yat Sun Or
- Main IPC: A61K31/7048
- IPC: A61K31/7048 ; C07H17/08 ; A61P31/04

Abstract:
The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit superior antibacterial properties, particularly against Haemophilus influenzae. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
Public/Granted literature
- US08383785B2 Anti-bacterial activity of 9-hydroxy derivatives of 6,11-bicyclolides Public/Granted day:2013-02-26
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