发明申请
US20090286965A1 MUTANT GROWTH FACTORS WITH ALTERED RECEPTOR SPECIFICITIES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
有权
具有改变的受体特异性的重要生长因子和包含其的药物组合物
- 专利标题： MUTANT GROWTH FACTORS WITH ALTERED RECEPTOR SPECIFICITIES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
- 专利标题（中）： 具有改变的受体特异性的重要生长因子和包含其的药物组合物
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申请号： US12159854申请日： 2007-01-09
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公开(公告)号： US20090286965A1公开(公告)日： 2009-11-19
- 发明人: Toru Imamura , Nozomi Tsujino , Masashi Suzuki , Masahiro Asada
- 申请人： Toru Imamura , Nozomi Tsujino , Masashi Suzuki , Masahiro Asada
- 优先权： JP2006-004210 20060111
- 国际申请： PCT/JP2007/050070 WO 20070109
- 主分类号： C07K14/50
- IPC分类号： C07K14/50
摘要：
Disclosed is a mutant protein having an altered fibroblast growth factor receptor specificity, which is produced by deleting one or more amino acid residues from the N-terminus of the amino acid sequence of naturally secreted fibroblast growth factor 18. The protein mutant can be used in a pharmaceutical composition for regulating hair regeneration or growth or a pharmaceutical composition for regulating bone or cartilage formation.
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