发明申请
- 专利标题： LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS
- 专利标题（中）： LACTAM化合物及其作为药物的用途
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申请号： US12252700申请日： 2008-10-16
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公开(公告)号： US20090291946A1公开(公告)日： 2009-11-26
- 发明人: Wenqing Yao , Chunhong He , David M. Burns , Jincong Zhuo , Meizhong Xu , Colin Zhang , Ding-Quan Qian , Brian Metcalf
- 申请人： Wenqing Yao , Chunhong He , David M. Burns , Jincong Zhuo , Meizhong Xu , Colin Zhang , Ding-Quan Qian , Brian Metcalf
- 申请人地址： US DE Wilmington
- 专利权人： INCYTE CORPORATION
- 当前专利权人： INCYTE CORPORATION
- 当前专利权人地址： US DE Wilmington
- 主分类号： A61K31/438
- IPC分类号： A61K31/438 ; C07D471/10 ; A61K31/5355 ; A61K31/506 ; A61K31/517 ; A61K31/496 ; A61P3/00 ; A61P9/00
摘要：
The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
公开/授权文献
- US08110581B2 Lactam compounds and their use as pharmaceuticals 公开/授权日：2012-02-07
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