发明申请
US20090298926A1 PROCESS FOR THE PURIFICATION 10-DEACETYBACCATINE III FROM 10-DEACETYL-2-DEBENZOYL-2-PENTENOYLBACCATINE III
有权
从10-脱乙酰基-2-苯甲酰基-2-苯基氨基乙酰胺III中纯化10-DEACETYBACCATINE III的方法
- 专利标题： PROCESS FOR THE PURIFICATION 10-DEACETYBACCATINE III FROM 10-DEACETYL-2-DEBENZOYL-2-PENTENOYLBACCATINE III
- 专利标题（中）： 从10-脱乙酰基-2-苯甲酰基-2-苯基氨基乙酰胺III中纯化10-DEACETYBACCATINE III的方法
-
申请号： US11918283申请日： 2006-04-07
-
公开(公告)号： US20090298926A1公开(公告)日： 2009-12-03
- 发明人: Bruno Gabetta , Andrea Gambini
- 申请人： Bruno Gabetta , Andrea Gambini
- 优先权： ITMI2005A000614 20050412
- 国际申请： PCT/EP2006/003162 WO 20060407
- 主分类号： A61K31/337
- IPC分类号： A61K31/337 ; C07D305/14
摘要：
A process for the preparation of 10-deacetyl-7,10-bis-trichloroacetylbaccatine III with HPLC purity higher than 99% and free from 2-debenzoyl-2-pentenoylbaccatine III by purification of 10-deacetyl-7,10-bis-trichloroacetylbaccatineIII followed by alkaline hydrolysis of the protecting groups in position 7 and 10.
公开/授权文献
信息查询
