发明申请
- 专利标题: DETECTION OF THE DETACHMENT OF IMMOBILIZED CONTRAST AGENT IN MEDICAL IMAGING APPLICATIONS
- 专利标题(中): 检测医疗成像应用中静止对比剂的分离
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申请号: US12520839申请日: 2007-12-21
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公开(公告)号: US20090304593A1公开(公告)日: 2009-12-10
- 发明人: Peter Frinking , Tristan Messager , Marcel Arditi , Nicolas Rognin
- 申请人: Peter Frinking , Tristan Messager , Marcel Arditi , Nicolas Rognin
- 申请人地址: NL Amsterdam
- 专利权人: BRACCO INTERNATIONAL BV
- 当前专利权人: BRACCO INTERNATIONAL BV
- 当前专利权人地址: NL Amsterdam
- 优先权: EP06126850.4 20061221
- 国际申请: PCT/EP07/64501 WO 20071221
- 主分类号: A61K49/00
- IPC分类号: A61K49/00 ; A61P43/00 ; G06K9/00 ; A61B8/00
摘要:
An embodiment of a solution is proposed for imaging a body-part that is perfused with a contrast agent. A corresponding method includes the step of providing a sequence of input images (for example, acquired with an ultrasound scanner); the input images offer a digital representation over time of the body-part. Each input image includes a plurality of input values (i.e., pixel or voxel values); each input value is indicative of a response to an interrogation signal (such as an echo signal for ultrasound waves) of a corresponding location of the body-part, which possibly includes the contrast agent. The method further includes the step of generating at least one filtered image from a plurality of selected ones of the input images (such as all of them or a subset thereof). Each filtered image includes a filtered value for each of a plurality of selected ones of the locations (for example, in a region of interest, or ROI). The filtered value of each selected location is indicative of the contrast agent that leaves the selected location after being substantially stationary at the selected location for a period of time, which is comprised between a first non-zero threshold and a second threshold higher than the first threshold (such as because the contrast agent detaches from the location after having been immobilized thereon, or because it was moving very slowly). The filtered value is obtained by reducing, where present, a contribution of the contrast agent that is substantially stationary at the selected location along the selected input images for a period of time equal to or shorter than the first threshold, and by reducing a contribution of the contrast agent that is substantially stationary at the selected location along the selected input images for a period of time equal to or longer than the second threshold.
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